Ho Peng Yoke has published widely on Chinese alchemy, astronomy, divination and mathematics. He occupied senior academic positions in Singapore, Malaysia, Australia and Hong Kong before becoming the Director of the Needham Research Institute in 1990. On his retirement at the end of 2001 he became its Emeritus Director. He is an academician of the Australian Academy of the Humanities, Academia Sinica and the International Euro-Asia Academy of Science.