This book provides an in-depth examination of next-generation biomaterials that integrate dynamic responsiveness with regenerative medicine applications. The book highlights how 4D materials capable of shape transformation in response to stimuli such as pH temperature light or biochemical signals are revolutionizing tissue engineering and therapeutic delivery. It explores shape-changing scaffolds designed to mimic native tissue environments as well as advanced drug delivery platforms that enable controlled targeted and on-demand release of therapeutics. Multidisciplinary perspectives from bioengineering nanotechnology materials science and clinical research are presented to demonstrate translational potential. The text emphasizes the role of smart biomaterials in accelerating tissue repair enhancing biocompatibility and paving the way for personalized medicine. Serving as both a research reference and practical guide it outlines the future of regenerative strategies empowered by 4D innovation.
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