ADME Processes in Pharmaceutical Sciences

Absorption Distribution Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. Whereas primarily oriented to Pharmacy students and graduates it can also be useful for scientist from different fields elated to pharmaceutics and pharmacology. (e.g. material scientists material engineers medicinal chemists physicians) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and related biological background.Pedagogical features such as objectives keywords discussion questions summaries and case studies are included as teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters multi-drug resistance related to pharmacokinetic phenomena last generation pharmaceutical carriers (nanopharmaceuticals) in vitro and in vivo bioequivalence studies biopharmaceuticals pharmacogenomics drug-drug and food-drug interactions in silico and in vitro prediction of ADME properties or chronopharmacokinetic. In comparison with other similar textbooks around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume and is written with experts on the correspondent topic including industrial scientists and academics from USA and UK.Additionally each of the initial chapters dealing with the generalities of drug absorption distribution metabolism and excretion would include relevant classic examples related to each topic with appropriate illustrations. ADME Processes and Pharmaceutical Sciences is written as a core textbook for courses on pharmaceutical sciences: pharmacology pharmacokineticsdrug delivery biopharmaceutics drug design and medicinal chemistry courses.