<p>This reprint is a collection of articles belonging to the Special Issue <em>Advances in Metabolic Profiling of Biological Samples</em> of <em>Metabolites</em>. The Special Issue is dedicated to reviews and original articles covering the current methodological and technological advancements in the pre-analytical handling of biological samples sample preparation protocols analytical approaches for untargeted and targeted metabolic profiling and metabolite annotation tools.</p>
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