Ag & Au Nanoparticles - Aluminum Toxicity in Mice

Synthesis of noble metal nanoparticles such as silver gold platinum and palladium using plants or plant extracts have been suggested as possible ecofriendly alternatives to chemical and physical methods. Among the contaminants Aluminum(Al) is one of the white silvery metals abundantly distributed in the environment. Al accumulates in all tissues of the mammals including brain liver kidney heart blood and bone. Al is known to disrupt the various biochemical and physiological functions in humans. Bacopa monniera (Bm) is one of the miracle herb commonly grows in marshy areas throughout India. In the traditional Ayurvedic medicine it is used for treatment of ulcers tumours enlarged spleen indigestion inflammation leprosy anemia epilepsy and asthma. Hence the authors made an attempt to synthesize silver and gold nanoparticles by using Bacopa monniera. The structural morphological antimicrobial in vitro antioxidant activities of synthesized nanoparticles have been carried out and also the effect of these nanoparticles against aluminum induced toxicity has been studied in albino mice.