<p>• Applications of Information Theory to Epidemiology collects recent research findings on the analysis of diagnostic information and epidemic dynamics. • The collection includes an outstanding new review article by William Benish providing both a historical overview and new insights. • In research articles disease diagnosis and disease dynamics are viewed from both clinical medicine and plant pathology perspectives. Both theory and applications are discussed. • New theory is presented particularly in the area of diagnostic decision-making taking account of predictive values via developments of the predictive receiver operating characteristic curve. • New applications of information theory to the analysis of observational studies of disease dynamics in both human and plant populations are presented.</p>