<p>Cardiothoracic and pulmonary diseases are a significant cause of mortality and morbidity worldwide. The COVID-19 pandemic has highlighted the lack of access to clinical care the overburdened medical system and the potential of artificial intelligence (AI) in improving medicine. There are a variety of diseases affecting the cardiopulmonary system including lung cancers heart disease tuberculosis (TB) etc. in addition to COVID-19-related diseases. Screening diagnosis and management of cardiopulmonary diseases has become difficult owing to the limited availability of diagnostic tools and experts particularly in resource-limited regions. Early screening accurate diagnosis and staging of these diseases could play a crucial role in treatment and care and potentially aid in reducing mortality.&nbsp;Radiographic imaging methods such as computed tomography (CT) chest X-rays (CXRs) and echo ultrasound (US) are widely used in screening and diagnosis. Research on using image-based AI and machine learning (ML) methods can help in rapid assessment serve as surrogates for expert assessment and reduce variability in human performance.&nbsp;In this Special Issue Artificial Intelligence in Image-Based Screening Diagnostics and Clinical Care of Cardiopulmonary Diseases we have highlighted exemplary primary research studies and literature reviews focusing on novel AI/ML methods and their application in image-based screening diagnosis and clinical management of cardiopulmonary diseases. We hope that these articles will help establish the advancements in AI.</p>
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