Bio-potency of Isoniazid Based Compounds: Recent Progress

Isoniazid otherwise known as isonicotinyl hydrazide is an antibiotic used for the treatment of latent and active tuberculosis infections. It is one of the oldest drugs for the treatment of TB. The chemistry of isoniazid and its derivatives are truly exciting owing to their plethora of applications in diverse and promising areas which is undoubtably beneficial to the humankind. Most importantly the therapeutic uses of these compounds e.g microbicidal antioxidant anticancer and DNA binding applications are cardinal in human healthcare system. Furthermore the combined effect of isoniazid with rifampicin ketoprofen etc. is also reported.