Pregnancy is a state of immunologic tolerance and when these tolerance mechanisms has broken it may be responsible for pregnancy loss or spontaneous abortion. This work tries to shed light on determination of biochemical and immunological markers in diagnosis of pregnancy complications which causes recurrent pregnancy loss such as; Anti-cardiolipin (ACA) Anti –dsDNA activity of Alanine Aminopeptidase (AAP) and its isoenzymes purified from urine of aborted women.
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