Bioinorganic Chemistry

<p>of metal ions in biological systems including their importance in structural catalytic and regulatory functions within living organisms.</p><p>Metalloenzymes and Catalysis: Discuss metalloenzymes enzymes that contain metal ions as cofactors and their role in catalyzing essential biochemical reactions such as oxygen transport (hemoglobin) electron transfer (cytochromes) and nitrogen fixation (nitrogenase).</p><p>Metal Ion Transport and Storage: Explore mechanisms for metal ion transport and storage in biological systems including proteins like ferritin for iron storage and transferrin for iron transport essential for maintaining metal ion homeostasis.</p><p>Bioinorganic Medicinal Chemistry: Examine the use of metal-based compounds in medicine including platinum-based drugs like cisplatin for cancer treatment and contrast agents used in imaging techniques such as MRI.</p><p>Photosynthesis and Electron Transfer: Discuss the role of metal ions in photosynthesis specifically in the electron transport chain and the oxygen-evolving complex which contains manganese and plays a critical role in converting light energy into chemical energy.</p><p>Analytical Techniques in Bioinorganic Chemistry: Highlight techniques used to study metal ions in biological systems such as X-ray crystallography electron paramagnetic resonance (EPR) and nuclear magnetic resonance (NMR) spectroscopy providing insights into metal binding and function.</p>