<p>Oxidative stress and in particular biologically relevant free radicals play an important role in redox signaling under physiological conditions. During inflammation their nanomolar concentrations can increase substantially with a corresponding increase in damage to biomolecules. Chemistry can have an important role in the search for oxidative stress and related biomarkers as well as in the search for molecular mechanisms in oxidative stress processes. Furthermore the modification of biomolecules&nbsp;can be used to identify biomarkers in vitro and in vivo and for the identification of antioxidant activities. This Special Issue of <em>Biomolecules</em> titled Biomarkers of Oxidative and Radical Stress showcases a remarkable range of research pertaining to these areas. This collection contains papers presenting research on oxidizing DNA proteins and lipids as well as antioxidant protection.</p>
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