Biomolecular Action of Ionizing Radiation

<p>Embracing the transformation of radiation sciences by the recent surge of developments in molecular biology this progressive text offers an up-to-date analysis of <i>in vitro</i> and <i>in vivo</i> molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications<b> Biomolecular Action of Ionizing Radiation </b>also presents a much needed in-depth perspective on clinical applications for the treatment of cancer and radiation injuries.</p><p>Based on a popular course given by the author at McGill Universitythe bookplaces the traditional tenets of radiation biology in the context of contemporary cell and molecular biology. Using terms that non-experts in molecular biology can understand it clarifies the underlying mechanisms of radiation effects on molecular interactions including signal transduction pathways modes of cell killing and non-targeted effects. The author subsequently associates key principles and advances with potential applications including the use of ionizing radiation as a cytotoxic and cytostatic agent and radiosensitization by targeting molecular intermediates or signaling molecules involved in radiation-induced processes. </p><p>Raising the standard for radiation biology texts that are currently available <b>Biomolecular Action of Ionizing Radiation </b>is an outstanding resource for advanced undergraduate and graduate students in medical physics radiation oncology radiation biology and those who have an interest in the radiation sciences and in cancer treatment.</p>