<p>The pestiviruses encompass some of the most economically important viral infections in the cattle swine and sheep industries worldwide. Discovered more than 70 years ago bovine viral diarrhea virus (BVDV) and classical swine fever virus (CSFV) were long the main concern but many new pestiviruses have emerged in recent years which may also present additional threats to biosecurity and food safety. This issue brings together contributions from multiple disciplines - virology immunology veterinary clinical medicine epidemiology and pathology - on the subject of BVDV and related pestiviruses and cover host-virus interactions virus-cell interactions cross-species transmission as well as the role of wildlife species as reservoirs of some of the pestiviruses.</p>
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