Brucella: Molecular Microbiology and Genomics

Brucella is a genus of Gram-negative facultative intracellular bacteria that are highly pathogenic for a variety of mammals including humans. Recently the World Health Organization cited brucellosis to be the worlds most widespread zoonosis. An important feature of the pathogenicity of these organisms is their ability to survive and replicate within the host macrophages. However the mechanism for this is unclear. In addition none of the classical bacterial virulence factors found in other bacter...See More