<p><span style=color: rgba(0 0 0 1); background-color: rgba(255 255 255 1)>The past decade has seen immunotherapy rise to the forefront of cancer treatment. This Special Issue of&nbsp;</span><em style=color: rgba(0 0 0 1)>Cancers</em><span style=color: rgba(0 0 0 1); background-color: rgba(255 255 255 1)>&nbsp;aims to elaborate on the latest developments cutting-edge technologies and prospects in cancer immunology and immunotherapy. Seventeen exceptional studies including original contributions and review articles written by international scientists and physicians primarily concerning the fields of tumor biology cancer immunology therapeutics and drug development comprise the main body of this Special Issue.</span></p>