<p>This Special Issue is conceived as a forum for basic translational and clinical research related to cell directional motility mechanisms and tumor cell migration. Under such a generic umbrella basic researchers in biology systems biology and other quantitative sciences as well as in physiology and pharmacology will have the opportunity to join clinical specialties in medical oncology biochemistry immunology and pathology. Such unique convergence of disciplines will enrich the panorama of a central characteristic of malignant tumors' cell motility.</p>
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