Chemistry and Biology of Beta-Lactams

<p>This new volume provides the most updated information about beta-lactams relating to both the pharmaceutical industry and synthetic chemistry. It provides the antibiotic activities as well as chemical reactivities of beta-lactams which are important because they are commonly applied as antibiotics in the treatment of bacterial infections. The volume provides comprehensive coverage of most of the known beta-lactam antibiotics with both structural and biological information antibiotic mechanisms self-defense mechanisms of bacteria nearly all known synthetic methods for the preparation of beta-lactams and possible reactions in which beta-lactams can participate.</p><p>Key features:</p><ul> <li>Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures CAS number IUPAC names and associated biological activities attached</li> <li>Offers a comprehensive and detailed collection of beta-lactamase databases</li> <li>Explains the self-defense mechanisms of bacteria for surviving including the formation of biofilm and conversion into L-form and secretion of beta-lactamase to deactivate the beta-lactam antibiotics</li> <li>Provides a comprehensive survey on the synthetic methods to make beta-lactams</li> <li>Gives all of the possible reactions involving beta-lactams as the starting materials</li> <li>Surveys over 1000 research works and includes all available DOI information</li> </ul><p>The volume is a valuable resource on the antibiotic activities as well as chemical reactivities of beta-lactams for researchers and scientists faculty and advanced students as well as for industry professionals working in medicinal and pharmaceutical chemistry organic chemistry organic synthesis heterocycles proteins and peptides.</p>