CHROMENE BASED SPIROCYCLIC MOLECULES AND BIOLOGICAL STUDIES

“CHROMENE BASED SPIROCYCLIC MOLECULES AND BIOLOGICAL STUDIES” has been divided into three chapters. Chapter I describes diastereoselective synthesis of novel spiro indanone fused pyrano[32-c]chromene derivatives following hetero-Diels-Alder reaction and in vitro anticancer studies. Chapter II describes with one-pot three-component regio- and sterospecific synthesis of spiro indanone pyrrolidine/piperidine fused nitrochromene derivatives through 13-dipolar cycloaddition reactions and chapter III describes base mediated green synthesis of enantiopure 2-C-spiro-glycosyl-3-nitrochromenes.