The extraction of the essential oil from the peels of Citrus x sp was performed using the hydrodistillation technique and its chemical constituents were characterized by Gas (GC-MS). The total phenolic content (CFT) was quantified and the total flavonoid content (CFLT).The physical-chemical parameters of refractive index .The nanoemulsions were formulated .the anti-inflammatory method of protein denaturation antioxidant capacity by the spectrophotometric and antiarthritic potentialby the BSA-induced .Through GC-MS it was possible to identify ten (10) constituents present in the essential oil of Citrus sp with limonene being the major component (70.25%) For CFT and CFLT 227.645 mg L-1 and the refractive index was and 86.57 mg L-1 were quantified respectively and the refractive index was quantified 1.475 For the results of the antioxidant capacity the nanoemulsions presentand 86.57 mg L-1 were quantifiedFor anti-arthritic activityit is noted that among the nine (9) synergies formulated S1 S6 and S8antioxidant capacity the nanoemulsions the best EC50 result of 9.10 for NOE3In anti-inflammatory activitysynergies S4 amounted to 4.63mg L-1.
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