Clinical and Biochemical Assessment of Ozonated Olive Oil Mixed Bone

The use of ozonated olive oil mixed with bone substitute to help in regeneration of intrabony peridontal defect. Within the limitations of the present study we can conclude that: The use of ozonized oil mixed bone graft showed little non-significant improvement in intrabony defect fill compared to the control graft defect fill. The use of ozonized olive oil in intra-bony defects increase GCF level and availability of bone morphogenic protein 2 significantly compared to the control non ozonized group. The use of ozonated olive oil once during mixing it with bone has no significant difference than subsequent use each week.