COINHERITANCE OF THALASSEMIA SYNDROMES WITH SICKLE CELL DISEASE

Sickle cell disease (SCD) is a chronic challenging global health problem. In Iraq it is highly prevalent in two Governorates: Basra in the extreme south and Dohuk in the extreme east-north. In Basra it represents a big burden to patients their families and the health care system. Lot of genetic (like β-chain haplotypes hemoglobin (Hb) F concentration and the α-thalassemia co-inheritance) and environmental factors contribute in affecting the disease behaviour.