Proteins have been broadly utilized in current detergents; there are not many examinations that manage chemical dose as its relationship with other. Catalyst based cleansers have been utilized for redesigning cleaning productivity of cleansers for a long time. This investigation for the most part centers around making a cleanser that is perfect condition amicable and productive with assistance of chemical lipase and watching its connection with surfactants i.e SDS CTAB Tween-20. Various examinations are directed at four unique temperatures i.e 25⁰C 30⁰C 35⁰C 40⁰C. The physico-chemical properties are examined to acquire the basic micelle focus (CMC) the thermodynamic parameters (∆H⁰m ∆S⁰m ∆G⁰m) of Sodium dodecyl sulfate (SDS) cetyltrimethyl ammonium bromide (CTAB) and Tween 20. The surface pressure reads are additionally accomplished for Sodium dodecyl sulphate (SDS) cetyltrimethyl ammonium bromide (CTAB) and Tween 20.