Comparison of Estimated Glomerular Filtration Rate (eGFR)

Several studies have shown the limitations of creatinine in the detection of early changes in glomerular filtration rate (GFR). Measurement of serum cystatin c has been proposed in assessment of renal status in order to improve management. The aim of this book is to compare the estimated glomerular rate GFR (eGFR) creatinine and eGFR cystatin c among apparently healthy individuals with a view to establishing the parameter that will detect the clinically significant level eGFR<60ml/mm/1.73m2 first. The eGFR using serum cystatin c revealed that 3% of the participants showed reduced renal function based on the KIDGO grouping. In conclusion eGFR cystatin c showed early stage of reduced renal function not detected by eGFR creatinine. This book will assist clinicians in proper patient management thus improve their quality of life.