Crack in Creation A

A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings. As a result dreams of genetic manipulation have become a stark reality the power to cure disease and alleviate suffering as well as to re-design any species including humans for our own ends. Jennifer Doudna is the co-inventor of this technology - known as CRISPR - and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg here she provides the definitive account of her discovery explaining how this wondrous invention works and what it is capable of. She also asks us to consider what our new-found power means how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers?|A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and contro...|The most important advance of our era. One of the pioneers of the field describes the exciting hunt for the key breakthrough and what it portends for our future|Too important … What may happen thanks to Doudna’s [discovery] is dizzying … for her this is the future of medicine. If she’s right then Crispr is about to make our present healthcare concerns look surprisingly trivial|One of the architects of this miraculous biological technique … explains the science clearly and excitingly as a kind of globalist detective story|Probably the greatest biological breakthrough since that of Francis Crick James Watson and Rosalind Franklin… We owe Doudna several times over – for her discovery for her zeal to take it from the lab into the clinic for her involvement in the ethical issues raised for her public engagement work and now for this book|An urgent plea from the celebrated biologist whose discovery enabled us to rewrite the code of life. The future is in our hands as never before and this book explains the stakes like no other|Urgent riveting and endlessly fascinating this book is destined to become an instant classic. Read it if you want to understand our biological future|In this wonderful book … Doudna’s and Sternberg’s simple but compelling exploration of this hugely important subject offers and excellent overview of this startling and unprecedented discovery|An exhilarating and frightening roadmap to our future by one of the most pioneering women in science|Jennifer Doudna is the true pioneer who built the bridge between the basic science of CRISPR and its diverse applications. Now is the time to read about the revolution that could change our world|A scientific thriller and a gripping read by a brilliant scientist|One of the most monumental discoveries in biology|A detailed account of the story so far. It may well end up being compared with the book that inspired a 12-year-old Doudna in the first place: James Watson’s The Double Helix … Packed with amazing female scientists it is thrilling generous and no less personal … We need scientifically informed conversations about what we should do next with these powers and Doudna’s book is a good place to begin|A welcome new contribution to the [gene editing] debate… She should be congratulated for being one of the very few scientists involved in a breakthrough to write a timely popular personal account… Doudna’s style more contemplative than Watson or Venter is just as effective at describing the increasingly frantic pace of life in the lab as researchers realise that epoch-making discoveries are in the offing. She tells the scientific back-story particularly well… The arguments are rehearsed with admirable clarity