Cytogenetics FISH and Molecular Testing in Hematologic Malignancies

<p>Cytogenetics fluorescence in situ hybridization (FISH) and molecular tests especially polymerase chain reaction (PCR) play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis as well as predict prognosis response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy.</p><p><em>Cytogenetics FISH and Molecular Testing in Hematologic Malignancies</em> provides a review of chromosomal and molecular changes in hematologic malignancies and correlates the karyotypic and genetic abnormalities with morphology immunophenotype and clinical data. With over 180 figures and diagnostic algorithms this text is essential reading for all pathologists hematopathologists hematologic oncologists cytogenetists cytogenetic technologists and cell biologists.</p>