Design and Analysis of Group-Randomized Trials

This text provides the most comprehensive treatment of the design and analytic issues involved in group-randomized trials. GRTs are comparative studies conducted to evaluate the effect of a health promotion intervention in which the units of assignment are identifiable groups (e.g. schools worksites) and the units of observation are members of those groups (e.g. students workers). The book reviews the underlying issues the most widely used research designs and analytic strategies. There is an emphasis on mixed-model regression with two chapters illustrating the analytic methods in SAS PROC MIXED and GLIMMIX. There is also a detailed chapter on power analysis and sample size calculation.