Patulin (PAT) is a mycotoxin produced by some filamentous fungi of the genera Aspergillus Penicillium Byssochlamys and Pacelomyces . These fungi can grow on fruits and vegetables but the apples and apple-based products are considered the main source of this mycotoxin and Penicillum expansum is the main responsible fungus .The main producer of PAT is the blue mold Penicillium expansum which is considered as a wound pathogen it is usually associated with fruits and vegetables especially in apple and its products.Different physical chemical and biological methods have been established for elimination of fungi producing mycotoxins and contamination of food and feed with toxigenic fungi.Biological methods using antagonist microorganisms has received large attention in recent years as a promising alternative which considers more safety in both human health and ecosystem.
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