In the present study an attempt was made to prepare characterize and evaluate a topical therapeutic system for anti-inflammatory purposes utilizing a natural permeation enhancer. Various hydrogel formulations were designed and optimized using varying concentrations of carbopol polymer.Natural remedies are often perceived as safer with fewer side effects compared to synthetic ones thus experiencing a growing demand in the global market. This study aims to demonstrate that natural permeation enhancers in gel formulations exhibit promising permeation enhancement properties.
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