Effect of bone bank processing on bmd histomorphometry of allograft

This book based on the thesis emphasises that bone mineral density should not be used as a sole predictor of bone strength. It is a scalar quantity and does not give information on the 3D structure of the bone. Rather Histomorphometry gives a much better picture as it is able to measure the bone microstructure and hence better predict the bone strength. However it is an in vitro method and not available readily. There is a need of development of newer in vivo modalities which are able to measure the bone microstructure and hence predict the propensity for fractures.