On-farm field experiments were conducted to assess the impacts of some nitrogen (N) and phosphorus (P) bio-chemical fertilization regimes on wheat grain yield and its components and harvest index of wheat cultivar Misr-1. Experiments were conducted in a farmer''s field El-Sheikh Essa Village Zagazig District Sharkia Governorate Egypt during the two successive winter seasons of 2012-2013 and 2013-2014.