Research report on Economic Strengthening (ES) to improve households’(HH) care for vulnerable children. Scanty information exists on outcomes beyond counting of program services. Outcomes on child well-being; health nutrition and protection are poorly understood. Knowledge gaps exists to inform stakeholders of interventions which could impact OVC well-being. Study assessed health nutrition and protection outcomes of OVC (6-59 months) in Migori. Study design was comparative cross-sectional survey with purposive and random sampling of 400 HH (200 intervention & 200 non-intervention). Quantitative and qualitative data was collected then analyzed using STATA and manual transcription. Chi-square and t-tests established that intervention HH OVC had significantly (P<0.05) better Health; {malaria (X2=32.806 P=0.00) diarrhea (X2=30.027 P=0.000) immunized (X2=27.845 P=0.000)} and Nutrition; {MUAC (t=-7.596 P=0.000) WAZ (t=-2.386 P=0.008) HAZ (t=-1.845 P=0.032)} and were better Protected from abuse (X2=22.809 P=0.000) and neglect (X2=1.88 P=0.170). It concluded that ES improved OVC well-being and recommended linkages with protection safety nets and further research on ES.