Effects of Purslane Ethanolic extract on doxorubicin-induced toxicity

Doxorubicin (DOX) an anthracycline antibiotic is a broad-spectrum antineoplastic agent which is commonly used in the treatment of uterine ovarian breast and lung cancers Hodgkin's disease and soft tissue sarcomas as well as in several other cancer types. The effect of doxorubicin intraperitoneal injection at dose level of 4 mg/kg b.w./week without or with oral administration of ethanolic purslane (Portulaca oleracea) shoot (leaves and stems) extract (50 mg/kg b.w./ day) or seed extract (50 mg/kg b.w.day) for 6 weeks was evaluated in adult male rats.