Wireless technologies have significantly influenced the development of new sensing concepts for continuous health monitoring and disease detection. Compared to wired solutions wireless sensors overcome limitations such as risk of infection and discomfort caused by tethered connections. Wireless systems are classified as passive (powerless) and active (powered). Activesolutions face significant challenges both in terms of power management and fabrication requiring the integration of complex electronic components and circuits. Furthermore active devices may require power source replacement which can lead to health risks and complications for the patient. In contrast passive devices present reduced complications thanks to their powerless nature and simpler architecture. Wireless devices typically rely on electromagnetic coupling interrogation for powering or data transmission. Electromagnetic waves while being a common approach for sensing interrogation are limited by overheating risks associated with high energy absorption and scattering in tissue. Moreover the development of customized receivers for these sensing applications requires significant design investment.Due to their mechanical nature acoustic waves achieve comparable penetration depths to electromagnetic waves at lower power levels. Furthermore standardized clinical equipment such as echographs can be utilized for interrogation in the MHz regime (ultrasound). Acoustic sensors based on ultrasound interrogation have already been explored but they are mostly limited by the spatial resolution of commercially-available transducers often insufficient to measure variations of biomedical parameters of interest (e.g. pressure temperature). This thesis presents a new approach to perform intracorporeal sensing investigating theadvantages of frequency resolution and ultrasound interrogation. In particular this is achieved exploiting the high resonant states generated by an acoustic metamaterial. Meta
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