<p>The extraction of active ingredients from vegetable matter is one of the most attractive research fields in the literature. A perspective that promotes this large interest is the possibility of identifying eco-friendly and innovative processes active products and materials. However care must be taken in selecting process arrangements and extraction conditions to minimize the co-extraction of undesired compounds. The analysis of the composition of the extracted compounds by chromatography mass spectrometry and related techniques is a relevant step in determining the performance of the extraction process and the purity of the extracted compounds to be used for pharmaceutical applications.</p><p>This reprint includes 10 Research papers 1 Communication and 1 Review and reports innovative extraction techniques and advanced analytical methods used for the recovery and the identification of high-added value compounds from vegetable matter.</p>