Erythromycin producing bacteria Saccharopolyspora erythraea strain MTCC No. 1103 was purchased from MTCC Chandigarh. Sporulation of this bacteria was done on Oat meal Agar medium at a temperature of about 30?C. Optimization of the fermentation conditions was performed with different parameterlike temperature pH time etc. Fermentative production of erythromycin gave best results with a temperature of 30?C at a pH of 7.5 in 5 days. Further research works are going on process optimization with shake flask & bioreactors.
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