Formulation and Evaluation of Nifidipine capsule by Liquisolid compact

The most appropriate and convenient dosage form is a capsule. the capacity to cover up bad tastes and smells. They may improve the active ingredients' bioavailability and readily dissolve in the digestive tract's gastric juices. The calcium-channel blocker nifedipine is frequently used to treat systemic hypertension and angina pectoris. Nifedipine has a relatively short half-life of two hours and is completely soluble in water. As a result it is generally acknowledged that the most effective form of Nifedipine for routine hypertension treatment is in capsule form. The primary goal of the research was to create and assess a hard gelatin capsule dosage form of nifedipine which is used to treat hypertension. To improve the solubility of the medication polymers like Transcutol and PEG 400 were used.