Gintonin against age-related Neurodegenerative diseases

In this book we have collected the current studies highlighting the protective potentials of gintonin in the management of different neurodegenerative conditions. The gintonin is a non-carbohydrate/ saponin that has been characterized as lysophosphatidic acid receptors (LPA Receptor) ligand. Gintonin may cause a significant elevation in calcium level [Ca2+]i intracellularly which promotes the calcium-mediated cellular effects via the modulation of ion channels and cell surface receptors regulating the inflammatory effects. Years of research have suggested that gintonin has antioxidant and anti-inflammatory effects against different models of neurodegeneration and these effects may be employed to tackle the neurological changes. Therefore we collected the main scientific findings and comprehensively presented them covering their preparation absorption and its effects against neurological disorders aiming to provide insight for the possible use of gintonin in the management of neurodegenerative conditions.