Growth Factors

Regenerative endodontic therapy aims to repair the pulp-dentin complex in immature permanent teeth with necrotic pulp that has been harmed by trauma infection or developmental abnormalities. This intricate process is regulated by a complex signalling network involving numerous growth factors. Using both endogenous and exogenous growth factor sources can open up interesting possibilities for new biological strategies for tissue engineering and dentin-pulp complex healing. The understanding of the precise functions of these growth factors during dental tissue regeneration and repair are essential.