Periodontal regeneration refers to the biological process through which lost or injured periodontal structures-such as alveolar bone periodontal ligament and cementum-are restored in both form and function. This process is distinct from simple repair because regeneration requires the precise reconstitution of these specialized tissues. Tissue regeneration is inherently complex involving a well-coordinated cascade of cellular activities: cell adhesion migration proliferation and differentiation. Various strategies have been developed to support and enhance this regenerative capacity. Among the most widely employed methods are the use of bone graft materials in combination with Guided Tissue Regeneration.
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