Handbook of Proteases in Cancer

<p>This handbook provides comprehensive coverage of the role of proteases and the associated biochemical pathways in cancer development and metastasis. Proteases make up about 2% of the human genome and play a critical role in the tumor microenvironment. <em>Handbook of Proteases in Cancer: Cellular and Molecular Aspects</em> introduces the major classes of proteases and the signal transduction mechanisms associated with cancer initiation and progression. It discusses the role of inflammation and immune responses in proteases-induced cancer. The book covers cancer-induced gene expression and apoptotic and necrotic pathways in cancer. This is useful for researchers and professionals in cancer research biochemistry and physiology. </p><p><strong>Key Features</strong></p><p>• Provides insights on the roles of proteases and anti-proteases in the tumor microenvironment.</p><p>• Covers various cancer-induced apoptotic and necrotic pathways.</p><p>• Discusses the mechanisms by which proteases induce an increase in inflammation immune</p><p>response and gene expression.</p><p>• Covers the function of protease-activated receptors in cancer.</p><p>• Reviews the different gene expression pathways and the ways they become erratic during</p><p>protease-induced cancer.</p>