<p>Growing evidence shows that a dietary pattern inspired by Mediterranean diet<br />principles is associated with numerous health benefits. A Mediterranean-type<br />diet has been demonstrated to exert a preventive effect toward cardiovascular<br />diseases in both Mediterranean and non-Mediterranean populations. Part of<br />these properties may depend on a positive action toward healthier metabolism<br />decreasing the risk of diabetes and metabolic-syndrome-related conditions.<br />Some studies also suggested a potential role in preventing certain cancers. Finally<br />newer research has showed that a higher adherence to the Mediterranean diet is<br />associated with a lower risk of cognitive decline depression and other mental<br />disorders. Overall a better understanding of the key elements of this dietary<br />pattern the underlying mechanisms and targets are needed to corroborate<br />current evidence and provide insights on new and potential outcomes.This<br />Special Issue welcomes original research and reviews of literature concerning<br />the Mediterranean diet and various health outcomes:Observational studies on<br />established nutritional cohorts (preferred) case-control studies or population<br />sample on the association with non-communicable diseases;Level of evidence<br />on the association with human health including systematic reviews and metaanalyses;<br />Evaluation of application of Mediterranean diet principles in non-<br />Mediterranean countries;Description of mechanisms of action pathways and<br />targets at the molecular level including interaction with gut microbiota.</p>
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