<p><em>Helicobacter pylori</em> is one of the most common infections in the world affecting roughly half of all humans. Although it is not an infection that causes death immediately after infection it is one of the largest emerging infectious diseases in the history of humankind causing a wide variety of diseases and in the long term serious complications such as stomach cancer. This Reprint contains empirical studies and reviews regarding the diagnosis treatment complications and management of <em>H. pylori</em> infection including new diagnostic methods effective eradication regimens the management of gastric cancer and other topics.</p>