Hepatic Encephalopathy

<p>Hepatic encephalopathy (HE) is a complex neurological syndrome characteristic of patients with liver disease that causes a wide and complex spectrum of nonspecific neurological and psychiatric manifestations ranging from a subclinical entity such as minimal or covert hepatic encephalopathy to a deep form in which a complete alteration of consciousness can be observed: overt hepatic encephalopathy. Both minimal and overt hepatic encephalopathy have a high impact on patients caregivers and national health services driving substantial consumption of economic resources. In this Special Issue we discussed the current state-of-the-art research address ongoing knowledge gaps and ongoing controversies related to the pathogenesis diagnosis and therapeutic management of hepatic encephalopathy.</p>