Fabrication of new nanoparticles (NPs) and exploring their wide range of application have become extensive areas of research in the chemical biological electronic science and technology. Chemical reactivity of a bulk inorganic reagent can be significantly improved on transition to their low-dimensional NPs possessing highly active surface. Potassium permanganate is an inexpensive oxidizing agent. Unfortunately its strong oxidizing property prevents it from diverse utility in organic synthesis. This book presents a novel synthetic protocol for fabrication of High-valent Manganese Nanoparticle and its application for in-situ generation of Nitrile Oxides and their 13-DC to synthesize isooxazoline and isoxazole moiety from very sensitive carbohydrate precursors. Low reaction time simplicity and necessity of small amounts of metal oxidant are some of the other features of this synthetic strategy.
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