Histiocytic Disorders of Children and Adults

This comprehensive reference on histiocytic disorders considers the genetics pathophysiology and clinical management of this wide range of diseases. It covers all aspects of hystiocytic disorders--from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis to the uncommon cutaneous and extracutaneous histiocytic disorders. Current views on the function of normal histiocytes in the immune system the pathogenesis underlying genetic defects clinical presentation treatment controversies in therapy salvage therapies and the late consequences are also presented.