This book looks at the histologic outcomes of the commonly seen cryotherapy-ineligible lesions in the Cervical Cancer Prevention Progam in Zambia. The need to know what kind of abnormal cervicography requires to have histologic valuation is vital particularly in he the low economic situations. Sending all abnormal lesions for histology is costly leads to over treatment and does not reduce the incidence of cervical cancer. Conversely using a very stringent criteria to send abnormal lesions for histology may lead to inadvertent missing of cancer cases. An accurate criteria for determining which lesions are cryotherapy-ineligible and therefore requiring histological examination cannot be overemphasised.