Hodgkin's disease (HD) accounts for 6% of childhood tumors. A disease of older children and adolescents it is quite exceptional before the age of 2 and its frequency increases with age. The prognosis for MDH has improved considerably in recent decades. In developed countries long-term survival has risen from 40% in the 60s to over 90% in the 90s making this hemopathy a model of success in pediatric oncology. These results have been achieved thanks to the identification of prognostic factors that have enabled therapeutic protocols to be adapted.