Ibuprofen with new derivatives

In this book 5-membered-ring of heterocyclic compounds have been prepared by reaction of Schiff base derivatives of Ibuprofen with mercapto-acetic acid . The study aimed to synthesize derivatives of ibuprofen with more potency and to decrease the drug''s potential side effects a new series of 4-thiazolidinone derivatives of ibuprofen was synthesized VI a-e . The characterization of the titled compounds they were identified on the basis of their spectral FTIR 1HNMR technique and by measuring the physical properties.