Immunohistochemical Expression of CMV pp65 in Childhood Hepatitis

Cytomegalovirus (CMV) is the largest member of betaherpesviridae. CMV infection is the main cause of non A‐G viral hepatitis. CMV hepatitis is relatively common in early ages especially in early infancy and its important since it might result in cirrhosis and even death. This study was performed to determine the role of CMV in children with hepatitis those are serologically negative for hepatitis B and C by detection for the presence of CMV protein (pp65) in liver tissue by using immunohistochemistry.