Inhibitory effectof aqueous extract of different parts of Unripepawpaw

Unripe pawpaw plant is known to be very rich in bioactive phytochemicals and its fruits have been an important ingredient in folklore medicine for the treatment of diabetes mellitus but there is limited information on the possible mechanism of action by which it exerts this therapeutic effect.From this researchunripe pawpaw parts are rich sources of polyphenolics such as sinapinic acid 2-phenyl-6I-O-beta-D-glucoside O-coumaric acid epicatechin quercetin luteolin ferulic acid kaempferol and caffeic acid; and alkaloid such as carpaine with inhibitory activities against key enzyme linked to type 2 diabetes (α-amylase and α-glucosidase).